Sandesh Gawali

expert panel

AI infrastructure spending has entered an era of historic scale. Microsoft, Google, Amazon and others have collectively committed hundreds of billions of dollars to expand compute capacity, even as analysts warn that parts of the market may be racing ahead of sustainable demand. For enterprise leaders outside Big Tech, the stakes are just as high, but the margin for error is far smaller. While AI investment continues to accelerate, many organizations struggle to connect infrastructure outlays to near-term financial returns, raising concerns about capital efficiency and long-term value creation. Members of the Senior Executive AI Think Tank—a curated group of executives and leaders shaping enterprise AI strategy—argue that the debate should not center on whether to invest, but how. What follows is a playbook drawn directly from their insights—detailing how seasoned leaders evaluate billion-dollar bets, stage risk intelligently and ensure AI infrastructure becomes a durable advantage rather than an expensive monument to hype.

expert panel

The launch of the White House’s Genesis Mission represents a bold federal effort to leverage artificial intelligence for scientific discovery, national competitiveness and economic growth. Announced in November 2025 via executive order, the Genesis Mission aims to create an integrated experimentation platform by linking federal datasets, high-performance computing and public-private partnerships to accelerate AI-driven breakthroughs across biotechnology, energy, semiconductors and more. As this national initiative unfolds, questions about equitable access, anti-competitive risk and inclusive governance have emerged from both industry and policy communities. Ensuring that smaller players—startups, academic labs and emerging innovators—have a fair seat at the table is not just an ethical imperative but a strategic one if the United States wants sustained innovation and economic vibrancy. Members of the Senior Executive AI Think Tank—experts in machine learning, enterprise AI and AI strategy—offer frameworks and strategies that federal leaders can adopt to prevent the Genesis Mission from becoming a vehicle that reinforces incumbent dominance rather than broad-based innovation.